Effect of the peptide moiety of Lipid II on bacterial transglycosylase

Angew Chem Int Ed Engl. 2012 Oct 1;51(40):10123-6. doi: 10.1002/anie.201204038. Epub 2012 Sep 5.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteria / drug effects*
  • Bacteria / enzymology*
  • Binding Sites
  • Cell Wall / chemistry
  • Cell Wall / drug effects
  • Cell Wall / metabolism
  • Drug Design*
  • Glycosyltransferases / antagonists & inhibitors*
  • Glycosyltransferases / chemistry
  • Glycosyltransferases / metabolism*
  • Peptides / pharmacology*
  • Structure-Activity Relationship
  • Uridine Diphosphate N-Acetylmuramic Acid / analogs & derivatives*
  • Uridine Diphosphate N-Acetylmuramic Acid / chemistry

Substances

  • Peptides
  • Uridine Diphosphate N-Acetylmuramic Acid
  • muramyl-NAc-(pentapeptide)pyrophosphoryl-undecaprenol
  • Glycosyltransferases