A versatile fluorescence approach to kinetic studies of hydrocarbon autoxidations and their inhibition by radical-trapping antioxidants

Jason J Hanthorn; Evan Haidasz; Paul Gebhardt; Derek A Pratt

doi:10.1039/c2cc35214a

A versatile fluorescence approach to kinetic studies of hydrocarbon autoxidations and their inhibition by radical-trapping antioxidants

Chem Commun (Camb). 2012 Oct 18;48(81):10141-3. doi: 10.1039/c2cc35214a.

Authors

Jason J Hanthorn¹, Evan Haidasz, Paul Gebhardt, Derek A Pratt

Affiliation

¹ Department of Chemistry, Queen's University, 90 Bader Lane, Kingston, Ontario, Canada K1N 6N5.

PMID: 22952050
DOI: 10.1039/c2cc35214a

Abstract

We report a simple coumarin-triarylphosphine conjugate that undergoes fluorescence enhancement upon reaction with hydroperoxides and demonstrate its use to follow autoxidations of 7-dehydrocholesterol (at 37 °C) and hexadecane (at 160 °C) and their inhibition by antioxidants.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkanes / chemistry*
Coumarins / chemistry*
Dehydrocholesterols / chemistry*
Fluorescence
Fluorescent Dyes / chemistry*
Free Radical Scavengers / pharmacology*
Hydrogen Peroxide / chemistry*
Kinetics
Oxidation-Reduction
Phosphines / chemistry

Substances

Alkanes
Coumarins
Dehydrocholesterols
Fluorescent Dyes
Free Radical Scavengers
Phosphines
coumarin
Hydrogen Peroxide
7-dehydrocholesterol
n-hexadecane