Induction of autophagy does not alter the anti-tumor effects of HDAC inhibitors

Cell Death Dis. 2012 Sep 6;3(9):e387. doi: 10.1038/cddis.2012.128.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Apoptotic Protease-Activating Factor 1 / genetics
  • Apoptotic Protease-Activating Factor 1 / metabolism
  • Autophagy / drug effects*
  • Autophagy-Related Protein 5
  • Autophagy-Related Protein 7
  • Cell Line, Tumor
  • Depsipeptides / pharmacology
  • Depsipeptides / therapeutic use
  • Hematologic Neoplasms / drug therapy
  • Histone Deacetylase Inhibitors / pharmacology*
  • Histone Deacetylase Inhibitors / therapeutic use
  • Humans
  • Hydroxamic Acids / pharmacology
  • Hydroxamic Acids / therapeutic use
  • Mice
  • Microtubule-Associated Proteins / antagonists & inhibitors
  • Microtubule-Associated Proteins / genetics
  • Microtubule-Associated Proteins / metabolism
  • RNA Interference
  • RNA, Small Interfering / metabolism
  • Ubiquitin-Activating Enzymes / antagonists & inhibitors
  • Ubiquitin-Activating Enzymes / genetics
  • Ubiquitin-Activating Enzymes / metabolism
  • Vorinostat

Substances

  • APAF1 protein, human
  • ATG5 protein, human
  • Apoptotic Protease-Activating Factor 1
  • Autophagy-Related Protein 5
  • Depsipeptides
  • Histone Deacetylase Inhibitors
  • Hydroxamic Acids
  • Microtubule-Associated Proteins
  • RNA, Small Interfering
  • Vorinostat
  • romidepsin
  • ATG7 protein, human
  • Autophagy-Related Protein 7
  • Ubiquitin-Activating Enzymes