In this paper, the complete mitochondrial (mt) genome of Epinephelus awoara has been determined. The mt genome (16,802 bp) had the canonical mt gene content and arrangement, including 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and 2 non-coding regions. The overall base composition of the Heavy-strand is 28.47% A, 27.29% T, 16.54% G, and 27.70% C, with an AT content of 56.76%. It shared 92.6%, 85.5%, 86.1%, 84.9%, and 85.7% identities with that of Epinephelus akaara, Epinephelus bruneus, Epinephelus coioides, Epinephelus lanceolatus and Epinephelus moara, respectively.