Synthesis, structure and insecticidal activities of some novel amides containing N-pyridylpyrazole moeities

Molecules. 2012 Aug 31;17(9):10414-28. doi: 10.3390/molecules170910414.

Abstract

In our search for environmentally benign insecticides with high activity, low toxicity and low residue, a novel series of amides containing N- pyridylpyrazole moieties were designed and synthesized. The structures of the title compounds were characterized and confirmed by 1H-NMR and elemental analysis. Furthermore, the structure of compound 7l was determined by single crystal X-ray diffraction. The preliminary bioassay tests showed that some of them exhibited good insecticidal activities against Mythimna separata Walker, Plutella xylostella (Linnaeus, 1758) and Laphygma exigua Hübner.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemical synthesis*
  • Amides / chemistry*
  • Animals
  • Drug Design
  • Insecticides / chemical synthesis*
  • Insecticides / chemistry*
  • Molecular Structure
  • Moths*
  • Pyrazoles / analysis*
  • Pyrazoles / chemistry
  • Structure-Activity Relationship

Substances

  • Amides
  • Insecticides
  • Pyrazoles