Abstract
N-alkyl 2-[(2-oxo-2-aryl ethyl)amino] benzamide derivatives have been synthesized in high yields. This involves three-component reaction of isatoic anhydride, primary amines in the presence of 2-bromoacethophenone derivatives. The reaction workup is simple and the products can be easily separated from the reaction mixture.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetophenones / chemistry*
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Amines / chemistry*
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Benzamides / chemical synthesis*
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Benzamides / chemistry
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Green Chemistry Technology*
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Molecular Structure
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Oxazines / chemistry*
Substances
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2-bromoacethophenone
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Acetophenones
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Amines
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Benzamides
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Oxazines
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isatoic anhydride