Abstract
Graphene oxide shows stress-induced toxicity properties in vivo under different pathophysiological conditions. A dual-path chemical mechanism, involving the overproduction of hydroxyl radicals and the formation of oxidizing cytochrome c intermediates, is responsible for the toxicity properties.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Caenorhabditis elegans / drug effects*
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Caenorhabditis elegans / metabolism
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Cyclic N-Oxides / chemistry
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Graphite / chemistry*
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Graphite / toxicity*
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Nanostructures / toxicity*
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Oxidative Stress*
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Oxides / chemistry*
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Oxides / toxicity
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Polyethylene Glycols / chemistry
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Polylysine / chemistry
Substances
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5,5-dimethylpyrrolidin-2-one-1-oxide
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Cyclic N-Oxides
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Oxides
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Polylysine
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Polyethylene Glycols
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Graphite