Abstract
Two new compounds, named (3R,5R,8R)-3-O-[α-l-arabinopyranosyl (1 → 6)-β-d-glucopyranosyl]-5-hydroxymegastigma-6,7-dien-9-one (1) and (1R)-1-O-(β-d-glucopyranosyl)-phenylethylene glycol (2), were isolated from the extract of Rhodiola crenulata. Their structures were determined on the basis of various spectroscopic methods, including IR, HR-ESI-MS, 1D and 2D NMR, and chemical evidences. The cytotoxicity of these two compounds was evaluated by using MTT method.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Ethylene Glycols / chemistry
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Ethylene Glycols / isolation & purification*
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Ethylene Glycols / pharmacology
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Glucosides / chemistry
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Glucosides / isolation & purification*
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Glucosides / pharmacology
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Norisoprenoids / chemistry
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Norisoprenoids / isolation & purification*
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Norisoprenoids / pharmacology
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Nuclear Magnetic Resonance, Biomolecular
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Plant Roots / chemistry
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Rhodiola / chemistry*
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Saponins / chemistry
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Saponins / isolation & purification*
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Saponins / pharmacology
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Stereoisomerism
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Triterpenes / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology
Substances
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(1R)-1-O-(beta-D-glucopyranosyl)phenylethylene glycol
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(3R,5R,8R)-3-O-(alpha-L-arabinopyranosyl-(1-6)-beta-D-glucopyranosyl)-5-hydroxymegastigma-6,7-dien-9-one
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Ethylene Glycols
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Glucosides
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Norisoprenoids
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Saponins
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Triterpenes