Laugier-Hunziker syndrome

J Oral Maxillofac Pathol. 2012 May;16(2):245-50. doi: 10.4103/0973-029X.99079.

Abstract

Laugier-Hunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. They appear as macular lesions less than 5 mm in diameter. Laugier-Hunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential. Therefore, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management. Prompt clinical recognition also averts the need for excessive and invasive procedures and treatments. In India, the reported cases of this syndrome are very few. We provide a review of literature on Laugier-Hunziker syndrome with its differential diagnosis.

Keywords: Differential diagnosis; Laugier–Hunziker syndrome; mucocutaneous pigmentation; oral pigments.