Tuberculosis (TB) is a global anthropozoonotic infection that has raised awareness of the impact of disease at the human-livestock-wildlife interface. There are examples of transmission from livestock resulting in establishment of reservoirs in wildlife populations, and exposures from interactions between humans and wildlife that have resulted in disease outbreaks. A One Health approach is crucial to managing and protecting the health of humans, livestock, wildlife and the environment. Although still in its infancy in many areas of the world, the use of transdisciplinary teams to address wildlife-human-livestock boundary diseases will broaden the scope of options for solutions. This paper reviews some less commonly known examples of threats and outcomes using lessons learned from tuberculosis.
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