What is DIPNECH?

Clin Imaging. 2012 Sep-Oct;36(5):647-9. doi: 10.1016/j.clinimag.2011.11.011. Epub 2012 Jun 8.

Abstract

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare disorder that is being diagnosed more frequently with the increasing availability of advanced imaging and more accurate histopathology. It occurs most commonly in nonsmoking, middle-aged women. High-resolution computed tomography (HRCT) findings include mosaic attenuation due to constrictive bronchiolitis and small (<5 mm) randomly distributed pulmonary nodules. It is important to recognize this condition as it is considered a precursor of peripheral carcinoid tumors. This article will present a case of this uncommon condition with review of the literature, imaging findings, and clinical presentation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy
  • Female
  • Humans
  • Hyperplasia / pathology*
  • Lung Diseases / diagnostic imaging*
  • Lung Diseases / pathology
  • Neuroendocrine Cells / pathology*
  • Neurosecretory Systems / pathology*
  • Precancerous Conditions / diagnostic imaging*
  • Precancerous Conditions / pathology
  • Tomography, X-Ray Computed*