Some aspects of drug allergy in tuberculosis patients are given. The rate of drug allergy in these cases makes up 14.65% and tends to further increase. The frequency of such allergy depends on sex, age, specificity of a tuberculous process and underlying diseases. A list of the drugs more frequently causing allergic reactions was made. As far as antituberculosis institutions are concerned, it seems necessary to organize proper prevention, diagnosis and treatment of drug allergies that would meet modern requirements.