Abstract
A palladium-catalyzed regioselective C-H cyanation of heteroarenes was achieved using tert-butyl isocyanide as "CN" source, which provides a new and unique strategy for the preparation of (hetero)aryl nitriles. Indoles, pyrroles, and aromatic rings could be efficiently cyanated through C-H bond activation with high regioselectivity.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Catalysis
-
Indoles / chemical synthesis*
-
Indoles / chemistry
-
Molecular Structure
-
Nitriles / chemical synthesis*
-
Nitriles / chemistry
-
Palladium / chemistry*
-
Pyridines / chemistry
-
Pyrimidines / chemistry
-
Pyrroles / chemistry
-
Stereoisomerism
Substances
-
Indoles
-
Nitriles
-
Pyridines
-
Pyrimidines
-
Pyrroles
-
Palladium