Abstract
1-Thia-4b-aza-cyclopenta[b]fluorene-4,10-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that 1-thia-4b-aza-cyclopenta[b]fluorene-4,10-diones would be antifungal agents.
Copyright © 2012 Elsevier Ltd. All rights reserved.
MeSH terms
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Antifungal Agents / chemical synthesis*
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Antifungal Agents / chemistry
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Antifungal Agents / pharmacology*
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Dose-Response Relationship, Drug
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Fluorenes / chemical synthesis
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Fluorenes / chemistry
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Fluorenes / pharmacology*
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Fungi / drug effects*
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Fungi / growth & development
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Microbial Sensitivity Tests
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Molecular Structure
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Stereoisomerism
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Structure-Activity Relationship
Substances
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1-thia-4b-aza-cyclopenta(b)fluorene-4,10-dione
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Antifungal Agents
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Fluorenes