Parkinson's disease among American Indians and Alaska natives: a nationwide prevalence study

Mov Disord. 2012 Sep 15;27(11):1456-9. doi: 10.1002/mds.25153. Epub 2012 Aug 14.

Abstract

Background: The objective of this study was to determine the prevalence of Parkinson's disease (PD) among American Indian and Alaska Native (AI/AN) people.

Methods: We analyzed records for AI/AN people between 2002 and 2009 using inpatient and outpatient visit data from the Indian Health Service. Crude and age-adjusted prevalence, using the 2000 projected US population as the standard, was determined overall and by age group, sex, period, and region.

Results: An estimated 2613 AI/AN people carried the diagnosis of PD (crude prevalence, 143.8/100,000). Prevalence increased with age through 84 years. The age-adjusted rate was 355.7 and was higher among men than women (P < .0001). Rates differed by region (P < .0001).

Conclusions: Parkinson's disease is prevalent among AI/AN people. The prevalence increases with age, varies by geographic region, and is higher among men than women. Community-based studies are needed to define incidence, examine risk factors, and determine reasons for sex and regional differences in PD among AI/AN people.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Alaska / epidemiology
  • Cross-Sectional Studies
  • Female
  • Humans
  • Indians, North American / ethnology
  • Inuit / ethnology
  • Male
  • Middle Aged
  • Parkinson Disease / epidemiology*
  • Parkinson Disease / ethnology*
  • Retrospective Studies
  • Sex Factors
  • United States / epidemiology
  • United States / ethnology