Myeloid and lymphoid neoplasms with FGFR1 abnormalities: diagnostic and therapeutic challenges

Am J Hematol. 2013 May;88(5):427-30. doi: 10.1002/ajh.23296. Epub 2012 Aug 7.

Authors

Natasha M Savage¹, Ryan C Johnson, Jason Gotlib, Tracy I George

Affiliation

¹ Department of Pathology, Georgia Health Sciences University and Charlie Norwood VA Medical Center, Augusta, GA 30912, USA. nmsavage0630@gmail.com

PMID: 22886804
DOI: 10.1002/ajh.23296

No abstract available

Publication types

Case Reports

MeSH terms

Amino Acid Substitution
Bone Marrow / pathology
Chromosome Disorders / diagnosis
Fatal Outcome
Humans
Leukemia, Lymphoid / diagnosis*
Leukemia, Lymphoid / genetics
Leukemia, Lymphoid / pathology
Leukemia, Lymphoid / therapy
Leukemia, Myeloid / diagnosis*
Leukemia, Myeloid / genetics
Leukemia, Myeloid / pathology
Leukemia, Myeloid / therapy
Male
Middle Aged
Mutation*
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / pathology
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / therapy
Receptor, Fibroblast Growth Factor, Type 1 / genetics*
Receptor, Fibroblast Growth Factor, Type 1 / metabolism
Translocation, Genetic

Substances

FGFR1 protein, human
Receptor, Fibroblast Growth Factor, Type 1