Palladium-catalyzed atom transfer radical cyclization of unactivated alkyl iodide

Hui Liu; Zongjun Qiao; Xuefeng Jiang

doi:10.1039/c2ob25990g

Palladium-catalyzed atom transfer radical cyclization of unactivated alkyl iodide

Org Biomol Chem. 2012 Sep 28;10(36):7274-7. doi: 10.1039/c2ob25990g.

Authors

Hui Liu¹, Zongjun Qiao, Xuefeng Jiang

Affiliation

¹ Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanhai 200062, PR China.

PMID: 22886029
DOI: 10.1039/c2ob25990g

Abstract

A palladium-catalyzed atom transfer cyclization of unactivated alkyl iodide has been developed. A radical chain mechanism has been proposed for this transformation, which might not involve an alkylpalladium intermediate.

MeSH terms

Catalysis
Cyclization
Free Radicals / chemistry
Hydrocarbons, Iodinated / chemistry*
Molecular Structure
Organometallic Compounds / chemistry*
Palladium / chemistry*

Substances

Free Radicals
Hydrocarbons, Iodinated
Organometallic Compounds
Palladium