Development of refractory ascites during amiodarone therapy in a hemodialysis patient with nephrogenic and cardiogenic ascites

Ren Fail. 2012;34(8):1033-6. doi: 10.3109/0886022X.2012.705206.

Abstract

In this report, the clinical characteristics of a 65-year-old female patient with tricuspid regurgitation, ischemic cardiomyopathy, congestive heart failure, and chronic renal failure were retrospectively evaluated. Laboratory studies revealed cardiogenic ascites coincided with nephrogenic ascites and subclinical amiodarone-induced hypothyroidism. The ascites of the patient was responsive to management of congestive heart failure and therapeutic paracentesis during the first episode, add-on therapy with intensified hemodialysis during the second episode, and add-on therapy with low-dose eltroxin during the third episode. When nephrogenic ascites and cardiogenic ascites of maintenance hemodialysis patients become refractory, hypothyroidism should be examined in these patients.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amiodarone / adverse effects*
  • Ascites / etiology*
  • Female
  • Heart Failure / complications*
  • Heart Failure / therapy
  • Humans
  • Hypothyroidism / chemically induced*
  • Hypothyroidism / diagnosis
  • Kidney Failure, Chronic / complications*
  • Kidney Failure, Chronic / therapy
  • Paracentesis
  • Renal Dialysis
  • Retrospective Studies

Substances

  • Amiodarone