Fluoroquinolones, sulfonamides and macrolides were analyzed in soil samples collected from suburban areas in Tianjin, China. Fluoroquinolones were the predominant class of antibiotics. The mean total concentration of fluoroquinolones (33.56 μg/kg) was 30-fold higher than one of macrolides, which were the second dominant class antibiotics. Sulfonamides showed the lowest level in soil. The spatial distribution of fluoroquinolones showed wastewater irrigation was a potential source of antibiotics. The individual antibiotics levels were all below the trigger value (100 μg/kg) set by the Steering Committee of Veterinary International Committee, indicating the low risk for organisms in the agricultural soils of Tianjin.