Hypocalcemia induced by raloxifene

Curr Drug Saf. 2012 Apr;7(2):176-8. doi: 10.2174/157488612802715654.

Abstract

Raloxifene is an anti-resorptive agent used in postmenopausal osteoporosis. This is the first report of the occurrence of clinically significant hypocalcemia following raloxifene treatment in a patient with occult vitamin D deficiency. Since vitamin D deficiency is widely prevalent in the community, screening for vitamin D deficiency and its correction is advisable before the initiation of anti-resorptive therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Bone Density Conservation Agents / adverse effects*
  • Bone Density Conservation Agents / therapeutic use
  • Female
  • Humans
  • Hypocalcemia / chemically induced*
  • Mass Screening / methods
  • Osteoporosis, Postmenopausal / drug therapy
  • Raloxifene Hydrochloride / adverse effects*
  • Raloxifene Hydrochloride / therapeutic use
  • Vitamin D Deficiency / complications
  • Vitamin D Deficiency / diagnosis

Substances

  • Bone Density Conservation Agents
  • Raloxifene Hydrochloride