ERCP for the treatment of bile leak after partial hepatectomy and fenestration for symptomatic polycystic liver disease

World J Gastroenterol. 2012 Jul 28;18(28):3705-9. doi: 10.3748/wjg.v18.i28.3705.

Abstract

Aim: To describe endoscopic treatment of bile leaks in these patients and to identify risk factors in these patients which can predict the development of bile leaks.

Methods: Retrospective case-control study examining consecutive patients who underwent partial hepatectomy for polycystic liver disease (PLD) and developed a postoperative bile leak managed endoscopically over a ten year period. Each case was matched with two controls with PLD who did not develop a postoperative bile leak.

Results: Ten cases underwent partial hepatectomy with fenestration for symptoms including abdominal distention, pain and nausea. Endoscopic retrograde cholangiopancreatography (ERCP) showed anatomic abnormalities in 1 case. A biliary sphincterotomy was performed in 4 cases. A plastic biliary stent was placed with the proximal end at the site of the leak in 9 cases; in 1 case two stents were placed. The overall success rate of ERCP to manage the leak was 90%. There were no significant differences in age, gender, comorbidities, duration of symptoms, history of previous surgery or type of surgery performed between cases and controls.

Conclusion: ERCP with stent placement is safe and effective for management of post-hepatectomy bile leak in patients with PLD.

Keywords: Bile leak; Endoscopic retrograde cholangiopancreatography; Hepatectomy; Polycystic liver.

MeSH terms

  • Adult
  • Aged
  • Bile / metabolism*
  • Biliary Tract / pathology
  • Case-Control Studies
  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects*
  • Comorbidity
  • Cysts / surgery
  • Cysts / therapy*
  • Endoscopy / methods
  • Female
  • Gastroenterology / methods
  • Hepatectomy / methods*
  • Humans
  • Liver Diseases / surgery
  • Liver Diseases / therapy*
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Stents
  • Treatment Outcome

Supplementary concepts

  • Polycystic liver disease