Abstract
A new class of photochemically-activated CO-releasing molecule (photo-CO-RM), based on a Mn(CO)(4)(C^N) system, is reported in this study. Three CO molecules are released per CO-RM molecule. Complex 3 is a fast releaser, thermally stable in the dark and a viable therapeutic agent.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Carbon Monoxide / chemistry*
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Cell Line
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Cell Survival / drug effects
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Crystallography, X-Ray
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Manganese / chemistry*
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Mice
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Models, Theoretical
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Molecular Conformation
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Organometallic Compounds / chemical synthesis
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Organometallic Compounds / chemistry*
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Organometallic Compounds / pharmacology
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Ultraviolet Rays
Substances
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Organometallic Compounds
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Manganese
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Carbon Monoxide