This study aimed to investigate the psychometric properties of the Chinese translations of the Quick Inventory of Depressive Symptomatology (QIDS(16)), including the Clinician-Rated (QIDS-C(16)), Self-report (QIDS-SR(16)), and Interactive Voice Response (QIDS-SR-IVR(16)) formats. Thirty depressed Chinese Americans were assessed with Chinese translations of the QIDS-SR(16), QIDS-SR-IVR(16), and QIDS-C(16). Cronbach alpha estimates of internal scale consistency on the QIDS-SR(16), QIDS-SR-IVR(16), and QIDS-C(16) were 0.70, 0.74, and 0.79, respectively. Intercorrelations among the measures were QIDS-SR(16) and QIDS-SR-IVR(16), r = 0.79; QIDS-SR(16) and QIDS-C(16), r = 0.61; and QIDS-SR-IVR(16) and QIDS-C(16), r = 0.69 (all p values < 0.01). The areas under the curve for the receiver operating characteristics of the QIDS-SR(16) and QIDS-SR-IVR(16) were 0.78 (95% confidence interval, 0.61-0.95) and 0.81 (95% confidence interval, 0.65-0.96), respectively. The respective screening sensitivities/specificities were 0.73/0.74 and 0.86/0.58. The Chinese translations of the QIDS(16) have adequate psychometric properties and may be useful tools for depression screening.