Successful approach to treatment of Helicobacter bilis infection in X-linked agammaglobulinemia

J Clin Immunol. 2012 Dec;32(6):1404-8. doi: 10.1007/s10875-012-9750-8. Epub 2012 Jul 28.

Abstract

Helicobacter bilis, an unusual cause of chronic infections in patients with X-linked agammaglobulinemia (XLA), is notoriously difficult to diagnose and eradicate. Based on the limited number of cases reported worldwide, we highlight the typical features of H. bilis infection in XLA and provide a rational and successful approach to diagnosis and treatment of this challenging infection.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Agammaglobulinemia / complications
  • Agammaglobulinemia / diagnosis
  • Agammaglobulinemia / drug therapy*
  • Agammaglobulinemia / pathology
  • Anti-Bacterial Agents / therapeutic use*
  • Azithromycin / therapeutic use*
  • Chronic Disease
  • Ertapenem
  • Genetic Diseases, X-Linked / complications
  • Genetic Diseases, X-Linked / diagnosis
  • Genetic Diseases, X-Linked / drug therapy*
  • Genetic Diseases, X-Linked / pathology
  • Helicobacter / drug effects*
  • Helicobacter / genetics
  • Helicobacter / pathogenicity
  • Helicobacter Infections / complications
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / drug therapy*
  • Helicobacter Infections / pathology
  • Humans
  • Male
  • Ofloxacin / therapeutic use*
  • Phylogeny
  • Treatment Outcome
  • beta-Lactams / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • beta-Lactams
  • Azithromycin
  • Ofloxacin
  • Ertapenem

Supplementary concepts

  • Bruton type agammaglobulinemia