Mycobacterium tuberculosis pneumonia and bacteremia after allogeneic hematopoietic stem cell transplant: report of an instructive pediatric case

New Microbiol. 2012 Jul;35(3):353-7. Epub 2012 Jun 30.

Abstract

Pulmonary infections often complicate hematopoietic stem cell transplantation (HSCT) outcome. Uncommon aetiologies, like Mycobacterium tuberculosis, should be considered when the clinical conditions do not fully improve with standard antimicrobial therapy and microbiological evaluations are repeatedly negative for bacteria and fungi. We describe an interesting pediatric case of miliary lung tuberculosis after HSCT, which was successfully treated after administering the appropriate therapy.

Publication types

  • Case Reports

MeSH terms

  • Antibiotics, Antitubercular / therapeutic use
  • Bacteremia / microbiology*
  • Bacteremia / pathology
  • Child
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Male
  • Mycobacterium tuberculosis / isolation & purification
  • Mycobacterium tuberculosis / pathogenicity*
  • Pneumonia, Bacterial / drug therapy
  • Pneumonia, Bacterial / microbiology*
  • Pneumonia, Bacterial / pathology
  • Thorax / diagnostic imaging
  • Thorax / microbiology
  • Thorax / pathology
  • Tomography, X-Ray Computed / methods
  • Transplantation, Homologous
  • Treatment Outcome
  • Tuberculosis / drug therapy
  • Tuberculosis / microbiology*
  • Tuberculosis / pathology
  • Ultrasonography

Substances

  • Antibiotics, Antitubercular