Dendritic ventriloquism: inhibitory synapses throw their voices

Sarah Rieubland; Arnd Roth; Michael Häusser

doi:10.1016/j.neuron.2012.07.001

Dendritic ventriloquism: inhibitory synapses throw their voices

Neuron. 2012 Jul 26;75(2):190-3. doi: 10.1016/j.neuron.2012.07.001.

Authors

Sarah Rieubland¹, Arnd Roth, Michael Häusser

Affiliation

¹ Wolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK.

PMID: 22841305
DOI: 10.1016/j.neuron.2012.07.001

Abstract

In a theoretical study in this issue of Neuron,Gidon and Segev (2012) identify several new principles governing how inhibition interacts with excitation in active dendrites. They show that inhibitory synapses can interact with excitability at a distance, effectively "throwing their voices" in the dendritic tree, such that distributed inhibitory synapses can act synergistically to provide a global veto of dendritic excitability.

Publication types

Comment

MeSH terms

Dendrites / physiology*
Models, Neurological*
Neural Inhibition / physiology*
Neurons / physiology*
Synapses / physiology*

Grants and funding

094077/WT_/Wellcome Trust/United Kingdom