[Interaction of influenza A and B viruses with nanodiamond-based sorbents]

Vopr Virusol. 2012 Mar-Apr;57(2):9-13.
[Article in Russian]

Abstract

The paper presents data on the sorption of influenza A(H1N1), A(H1N1)v, A(H3N2) viruses, cDNA of A(H1N1)v and B viruses on nanodiamonds and furnace charge. The sorption of viruses occurred in different solutions at 4-37 degrees C during 10-20 min. The rate of sorption varied with the concentration of a sorbent in the solution and its structure, but did not with the antigenic formula of viruses or temperature. The sorption capacity of furnace charge towards influenza A and B viruses was higher than that of nanodiamonds. Nonviral proteins (bovine serum albumin and influenza virus antibodies) were found to be bound by both sorbents. Viral desorption did not take place in physiological solution at 4 and 22 degrees C for 48 hours.

Publication types

  • English Abstract

MeSH terms

  • Adsorption
  • DNA, Viral / chemistry*
  • DNA, Viral / isolation & purification
  • Humans
  • Influenza A virus / chemistry*
  • Influenza A virus / isolation & purification
  • Influenza B virus / chemistry*
  • Influenza B virus / isolation & purification
  • Influenza, Human / prevention & control
  • Influenza, Human / virology*
  • Nanodiamonds / chemistry*
  • Temperature
  • Time Factors

Substances

  • DNA, Viral
  • Nanodiamonds