[Loop diuretics: facts and fallacies]

Michele Meschi; Simona Detrenis; Laura Bianchi; Marcella Saccò; Marcello Bertorelli; Francesca Boffetti; Alberto Caiazza; Giorgio Savazzi

doi:10.1701/1127.12428

[Loop diuretics: facts and fallacies]

Recenti Prog Med. 2012 Jul-Aug;103(7-8):263-6. doi: 10.1701/1127.12428.

[Article in Italian]

Authors

Michele Meschi¹, Simona Detrenis, Laura Bianchi, Marcella Saccò, Marcello Bertorelli, Francesca Boffetti, Alberto Caiazza, Giorgio Savazzi

Affiliation

¹ Medicina Interna a Indirizzo Nefro-Cardiovascolare, Dipartimento de Medicina e Diagnostica, Ospecdale Santa Maria di Borgo val di Taro, Azenda USL di Parma. mmeschi@ausl.pr.it

PMID: 22825380
DOI: 10.1701/1127.12428

Abstract

Refractory edema is a clinical condition which recognises different etiologies and is characterized by decreased or absent diuretic response before the therapeutic goal is reached. Several pharmacokinetic and pharmacodynamic strategies are used in this setting, and further research is needed in order to optimize drug effectiveness.

Publication types

English Abstract
Review

MeSH terms

Drinking
Drug Administration Routes
Edema / drug therapy*
Edema / etiology
Furosemide / administration & dosage
Furosemide / pharmacology
Furosemide / therapeutic use
Heart Failure / complications
Heart Failure / physiopathology
Humans
Hydrostatic Pressure
Liver Cirrhosis / complications
Liver Cirrhosis / physiopathology
Loop of Henle / drug effects
Loop of Henle / physiopathology
Natriuresis / drug effects
Nephrotic Syndrome / complications
Nephrotic Syndrome / physiopathology
Sodium Potassium Chloride Symporter Inhibitors / administration & dosage
Sodium Potassium Chloride Symporter Inhibitors / pharmacology
Sodium Potassium Chloride Symporter Inhibitors / therapeutic use*
Water-Electrolyte Imbalance / etiology
Water-Electrolyte Imbalance / prevention & control

Substances

Sodium Potassium Chloride Symporter Inhibitors
Furosemide