Abstract
Background:
Myocardial ischemia during coronary spasm may generate malignant ventricular arrhythmias. The J-wave pattern was suggested to be a marker of a disorder associated with life-threatening arrhythmias.
Results:
We report the case of a patient with vasospastic angina and J-wave pattern in inferior and lateral leads associated with polymorphic ventricular tachycardia which was effectively treated only with quinidine-vasodilating drugs were not able to prevent the arrhythmia although they were effective in preventing ischemic events.
Conclusion:
The J-wave pattern in inferolateral leads may be a sign of electrical vulnerability to lethal ventricular arrhythmia in patients suffering from vasospastic angina--quinidine can effectively prevent such arrhythmias in these patients.
©2012, Wiley Periodicals, Inc.
MeSH terms
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Angina Pectoris, Variant / complications
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Angina Pectoris, Variant / diagnosis
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Angina Pectoris, Variant / therapy*
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Atrial Fibrillation / diagnosis*
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Atrial Fibrillation / etiology
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Atrial Fibrillation / surgery
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Atrial Flutter / diagnosis*
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Atrial Flutter / etiology
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Atrial Flutter / surgery
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Catheter Ablation / methods
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Combined Modality Therapy
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Defibrillators, Implantable*
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Drug Therapy, Combination
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Electrocardiography / methods
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Electrocardiography, Ambulatory / methods
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Exercise Test / methods
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Follow-Up Studies
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Humans
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Isosorbide / therapeutic use
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Male
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Middle Aged
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Molsidomine / therapeutic use
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Quinidine / therapeutic use*
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Risk Assessment
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Severity of Illness Index
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Tachycardia, Ventricular / complications
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Tachycardia, Ventricular / diagnosis
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Tachycardia, Ventricular / therapy*
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Treatment Outcome
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Verapamil / therapeutic use
Substances
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Verapamil
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Molsidomine
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Quinidine
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Isosorbide