The MRI features of histologically proven ovarian cystadenofibromas-an assessment of the morphological and enhancement patterns

Eur Radiol. 2013 Jan;23(1):48-56. doi: 10.1007/s00330-012-2568-1. Epub 2012 Jul 20.

Abstract

Objectives: To assess the morphological and enhancement features of histologically proven cystadenofibromas (CAFs) on magnetic resonance imaging (MRI).

Methods: Forty-seven histologically proven CAFs (42 benign, five borderline) were retrospectively reviewed. One benign CAF had a synchronous adenocarcinoma in the same ovary. The morphological, signal and enhancement characteristics on MRI were recorded.

Results: The mean long axis diameter of the CAFs was 80 mm. The contralateral ovary was abnormal in 45 % of cases. A solid component was seen in 85 %, which returned low T2-weighted signal in 75 % of CAFs. Septa were seen in 74 % and one CAF was purely cystic. The majority of solid components and septa demonstrated enhancement that was less than the myometrium. Wash-in rates (WIR) of the solid tissue were available for measurement in nine patients with an average WIR of 3.2 l/s.

Conclusion: This is the largest series describing MRI appearances of histologically proven CAFs. They are typically complex adnexal lesions containing septa, cystic components and solid tissue. The majority of solid components demonstrate low T2 signal and minimal enhancement. Almost half of the cases have an abnormal contralateral ovary.

MeSH terms

  • Adult
  • Aged
  • Contrast Media
  • Cystadenofibroma / pathology*
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted
  • Magnetic Resonance Imaging / methods*
  • Meglumine
  • Middle Aged
  • Organometallic Compounds
  • Ovarian Neoplasms / pathology*
  • Retrospective Studies

Substances

  • Contrast Media
  • Organometallic Compounds
  • Meglumine
  • gadoterate meglumine