Pd(II)-catalyzed ortho arylation of 2-arylbenzothiazoles with aryl iodides via benzothiazole-directed C-H activation

Qiuping Ding; Huafang Ji; Dan Wang; Yuqing Lin; Weihua Yu; Yiyuan Peng

doi:10.1016/j.jorganchem.2012.03.030

Pd(II)-catalyzed ortho arylation of 2-arylbenzothiazoles with aryl iodides via benzothiazole-directed C-H activation

J Organomet Chem. 2012 Jul 15;711(C):62-67. doi: 10.1016/j.jorganchem.2012.03.030.

Authors

Qiuping Ding¹, Huafang Ji, Dan Wang, Yuqing Lin, Weihua Yu, Yiyuan Peng

Affiliation

¹ Key Laboratory of Functional Small Organic Molecules, Ministry of Education and College of Chemistry & Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330022, China.

Abstract

A novel and efficient method for the arylation of 2-arylbenzothiazoles is described via C-H activation. The desired C(Ar)-C(Ar) bond formation proceeded efficiently with good functional-group tolerance and high regioselectivity. Proposed mechanism for the arylation of 2-arylbenzothiazole is depicted.