Fluorescent aplyronine a: intracellular accumulation and disassembly of actin cytoskeleton in tumor cells

Chembiochem. 2012 Aug 13;13(12):1754-8, 1702. doi: 10.1002/cbic.201200385. Epub 2012 Jul 16.

Authors

Masaki Kita¹, Kozo Yoneda, Yuichiro Hirayama, Kota Yamagishi, Yuki Saito, Yuka Sugiyama, Yoshihiro Miwa, Osamu Ohno, Maho Morita, Kiyotake Suenaga, Hideo Kigoshi

Affiliation

¹ Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571, Japan. mkita@chem.tsukuba.ac.jp

PMID: 22807378
DOI: 10.1002/cbic.201200385

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Actin Cytoskeleton / drug effects*
Actin Cytoskeleton / metabolism
Actins / antagonists & inhibitors*
Actins / metabolism
Animals
Antineoplastic Agents / chemistry*
Antineoplastic Agents / isolation & purification
Antineoplastic Agents / pharmacology
Aplysia / chemistry*
Apoptosis / drug effects
Biological Transport
Biotinylation
Cell Line, Tumor
Cell Survival / drug effects
Fluorescent Dyes
Humans
Inhibitory Concentration 50
Macrolides / chemistry*
Macrolides / isolation & purification
Macrolides / pharmacology
Mice
Microscopy, Fluorescence
Neoplasms / drug therapy
Neoplasms / pathology
Rhodamines / chemistry

Substances

Actins
Antineoplastic Agents
Fluorescent Dyes
Macrolides
Rhodamines
aplyronine A
tetramethylrhodamine