Attempted suicide under high dose dopaminergic therapy including apomorphine

Wien Klin Wochenschr. 2012 Jul;124(13-14):461-3. doi: 10.1007/s00508-012-0202-5. Epub 2012 Jul 15.

Abstract

Impulse control disorder during continuous subcutaneous apomorphine treatment (CAI) was recently reported. We describe a 54-year-old patient with familial Parkinson's disease, who after initiation of CAI in addition to high dose levodopa and amantadine, developed impulse control disorder (major financial loss related to risky transactions and self-medication), psychosis and depression, which lead up to attempted suicide. To our knowledge, this is the first case of attempted suicide under apomorphine treatment.

Publication types

  • Case Reports

MeSH terms

  • Apomorphine / administration & dosage
  • Apomorphine / adverse effects*
  • Apomorphine / therapeutic use*
  • Disruptive, Impulse Control, and Conduct Disorders / chemically induced*
  • Disruptive, Impulse Control, and Conduct Disorders / prevention & control*
  • Dopamine Agonists / administration & dosage
  • Dopamine Agonists / adverse effects
  • Dopamine Agonists / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / complications*
  • Parkinson Disease / drug therapy*
  • Suicide, Attempted / prevention & control*

Substances

  • Dopamine Agonists
  • Apomorphine