Abstract
The present report describes a very rare case of an aortic homograft valve endocarditis caused by Cardiobacterium hominis. The case was complicated by an agranulocytosis after 3 weeks of antibiotic treatment induced by ceftriaxone. Alternative oral treatment with ciprofloxacin and rifampicin was successful, no surgical intervention was needed and homograft function could be preserved.
MeSH terms
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Agranulocytosis / chemically induced*
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Agranulocytosis / complications
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Anti-Bacterial Agents / adverse effects*
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Anti-Bacterial Agents / therapeutic use
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Aortic Valve / abnormalities*
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Aortic Valve / transplantation*
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Aortic Valve Insufficiency / diagnosis
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Aortic Valve Insufficiency / surgery*
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Bacteremia / diagnosis
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Bacteremia / drug therapy
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Bioprosthesis
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Cardiobacterium*
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Ceftriaxone / adverse effects*
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Ceftriaxone / therapeutic use
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Drug Therapy, Combination
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Endocarditis, Bacterial / diagnosis*
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Endocarditis, Bacterial / drug therapy
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Follow-Up Studies
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Gram-Negative Bacterial Infections / diagnosis*
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Gram-Negative Bacterial Infections / drug therapy
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Heart Valve Prosthesis
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Humans
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Infant, Newborn
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Male
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Middle Aged
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Prosthesis Failure
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Recurrence
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Reoperation
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Transplantation, Homologous
Substances
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Anti-Bacterial Agents
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Ceftriaxone