Histomorphometric analysis of maxillary sinus augmentation using an alloplast bone substitute

J Oral Maxillofac Surg. 2012 Aug;70(8):1835-43. doi: 10.1016/j.joms.2012.04.034.

Abstract

Purpose: To evaluate the regenerative potential of a fully synthesized homogenous hydroxyapatite:β-tricalcium phosphate 60:40 alloplast material in sinus lift procedures.

Materials and methods: Hydroxyapatite:β-tricalcium phosphate was used for sinus floor augmentation. After 9 months, 12 biopsies were taken from 12 patients. Routine histologic processing was performed and specimens were analyzed using a light microscope and a digital camera.

Results: Histologic evaluation showed 26.4% newly formed bone, 27.3% residual graft material, and 46.3% bone marrow. The osteoconductive index was 33.5%.

Conclusions: Hydroxyapatite:β-tricalcium phosphate 60:40 alloplast material was found to be biocompatible and osteoconductive in maxillary sinus augmentation procedures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorbable Implants
  • Adult
  • Aged
  • Aged, 80 and over
  • Biocompatible Materials / therapeutic use
  • Biopsy / methods
  • Bone Marrow / pathology
  • Bone Regeneration / physiology
  • Bone Substitutes / therapeutic use*
  • Crowns
  • Dental Implantation, Endosseous / methods
  • Dental Prosthesis, Implant-Supported
  • Denture, Partial, Fixed
  • Female
  • Follow-Up Studies
  • Humans
  • Hydroxyapatites / therapeutic use
  • Image Processing, Computer-Assisted / methods
  • Male
  • Maxilla / pathology
  • Maxilla / surgery
  • Maxillary Sinus / pathology*
  • Middle Aged
  • Osseointegration / physiology
  • Osteogenesis / physiology
  • Sinus Floor Augmentation / methods*
  • Tomography, X-Ray Computed / methods

Substances

  • Biocompatible Materials
  • Bone Substitutes
  • Hydroxyapatites
  • hydroxyapatite-beta tricalcium phosphate