Abstract
It is shown that cytochrome c heme lyase (CCHL) attaches heme covalently to peptides composed of the N-terminal segment of cyt c fused to a non-heme containing protein, lending insight into the substrate specificity of CCHL and providing a new route to artificial heme proteins.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Cytochrome c Group / chemistry*
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Cytochrome c Group / metabolism
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Heme / chemistry*
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Heme / metabolism
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Horses
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Lyases / chemistry*
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Models, Molecular
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Molecular Sequence Data
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Peptides / chemistry*
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Peptides / metabolism
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Protein Processing, Post-Translational*
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Substrate Specificity
Substances
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Cytochrome c Group
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Peptides
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Heme
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Lyases
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cytochrome C synthetase