Management and recurrence of keratocystic odontogenic tumor: a systematic review

Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Oct;116(4):e271-6. doi: 10.1016/j.oooo.2011.12.028. Epub 2012 Jul 6.

Abstract

Objectives: The objective of this study was to evaluate the most up-to-date treatment modalities and respective recurrence rates for keratocystic odontogenic tumor (KCOT).

Study design: A systematic review of the literature from 1999 to 2010 was undertaken examining treatment and recurrence rates for KCOT. Four inclusion criteria were defined for articles to then be analyzed against 8 standards.

Results: Of the 2736 published articles, 8 met the inclusion criteria. When merging the data, enucleation and enucleation with adjunctive measures (other than Carnoy's solution) had recurrence rates of 25.6% and 30.3%, respectively. Marsupialization with adjunctive measures produced a recurrence rate of 15.8%, whereas enucleation with Carnoy's solution presented a recurrence rate of 7.9%. Only one resection case had recurrence (6.3%).

Conclusions: The enucleation technique with the use of adjunctive procedures (other than Carnoy's solution) provides a higher recurrence rate than any other treatment modality.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Acetic Acid / therapeutic use*
  • Chloroform / therapeutic use*
  • Ethanol / therapeutic use*
  • Humans
  • Jaw Neoplasms / pathology
  • Jaw Neoplasms / surgery*
  • Neoplasm Recurrence, Local*
  • Odontogenic Cysts / pathology
  • Odontogenic Cysts / surgery*
  • Odontogenic Tumors / pathology
  • Odontogenic Tumors / surgery*
  • Oral Surgical Procedures / methods*
  • Treatment Outcome

Substances

  • Carnoy's solution
  • Ethanol
  • Chloroform
  • Acetic Acid