Premature delivery due to intrauterine Candida infection that caused neonatal congenital cutaneous candidiasis: a case report

J Obstet Gynaecol Res. 2013 Jan;39(1):341-3. doi: 10.1111/j.1447-0756.2012.01938.x. Epub 2012 Jul 6.

Abstract

Congenital cutaneous candidiasis is a very rare disease with less than 100 cases published in the medical literature. Neonates having this disease present with systemic skin lesions caused by intrauterine Candida infections. We present a case of threatened premature delivery due to Candida chorioamnionitis, which caused both maternal postpartum endometritis and neonatal congenital cutaneous candidiasis. A 34-year-old woman who was admitted for fetal membrane bulging at 20 weeks of gestation underwent McDonald cervical cerclage. We diagnosed threatened premature delivery due to intrauterine infection; therefore, we terminated the gestation by cesarean section at 24 weeks of gestation. Fungi-like yeast was detected in infantile gastric juice. Histopathological findings of the placenta revealed that Candida albicans mycelium invaded the placenta, chorioamniotic membrane and umbilical cord.

Publication types

  • Case Reports

MeSH terms

  • Candidiasis / complications*
  • Candidiasis / pathology
  • Candidiasis / transmission*
  • Candidiasis, Cutaneous / congenital*
  • Candidiasis, Cutaneous / diagnosis
  • Female
  • Fetal Diseases / diagnosis*
  • Fetal Diseases / microbiology
  • Fetal Diseases / pathology
  • Humans
  • Infectious Disease Transmission, Vertical
  • Placenta / microbiology
  • Placenta / pathology
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Pregnancy Complications, Infectious / microbiology
  • Pregnancy Complications, Infectious / pathology
  • Premature Birth / etiology*
  • Premature Birth / microbiology
  • Premature Birth / pathology
  • Skin / microbiology*
  • Skin / pathology
  • Umbilical Cord / microbiology
  • Umbilical Cord / pathology
  • Uterus / microbiology
  • Uterus / pathology