A [24-MC-6] zinc metallacoronate with a nonsteroidal antiinflammatory drug as the constructing ligand

Alketa Tarushi; Filippos Kastanias; Vassilis Psycharis; Catherine P Raptopoulou; George Psomas; Dimitris P Kessissoglou

doi:10.1021/ic3010757

A [24-MC-6] zinc metallacoronate with a nonsteroidal antiinflammatory drug as the constructing ligand

Inorg Chem. 2012 Jul 16;51(14):7460-2. doi: 10.1021/ic3010757. Epub 2012 Jul 3.

Authors

Alketa Tarushi¹, Filippos Kastanias, Vassilis Psycharis, Catherine P Raptopoulou, George Psomas, Dimitris P Kessissoglou

Affiliation

¹ Department of General and Inorganic Chemistry, Faculty of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.

PMID: 22758372
DOI: 10.1021/ic3010757

Abstract

The interaction of ZnCl(2) with 2-dipyridylketonoxime (=Hpko) and flufenamic acid (=Hfluf) in a basic methanolic solution leads to the formation of a hexanuclear 24-membered metallacoronate, [Zn(6)(OH)(2)(pko)(4)(fluf)(6)] (1), with a [Zn-O-C-O] repeat unit and a nonsteroidal antiinflammatory drug as the constructing ligand. Compound 1 retains its structure in a dimethyl sulfoxide solution, as shown by (1)H NMR spectroscopy and molar conductance.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Inflammatory Agents, Non-Steroidal / chemical synthesis
Anti-Inflammatory Agents, Non-Steroidal / chemistry*
Crystallography, X-Ray
Flufenamic Acid / chemistry*
Ligands
Models, Molecular
Molecular Structure
Organometallic Compounds / chemical synthesis
Organometallic Compounds / chemistry*
Zinc / chemistry*

Substances

Anti-Inflammatory Agents, Non-Steroidal
Ligands
Organometallic Compounds
Flufenamic Acid
Zinc