Phenylethanoid glycosides from Monochasma savatieri and their anticomplement activity through the classical pathway

Planta Med. 2012 Aug;78(12):1381-6. doi: 10.1055/s-0032-1314982. Epub 2012 Jun 29.

Abstract

Five new phenylethanoid glycosides, savasides A-E (1-5), along with 6 known ones were isolated from the whole plant of Monochasma savatieri Franch. The structures of 1-5 were elucidated on the basis of spectroscopic data analysis. Moreover, all isolated compounds were evaluated for anticomplement activity through the classical pathway.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Complement Inactivator Proteins / chemistry
  • Complement Inactivator Proteins / isolation & purification
  • Complement Inactivator Proteins / pharmacology*
  • Complement Pathway, Classical / drug effects*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / pharmacology*
  • Erythrocytes / drug effects*
  • Glycosides / pharmacology*
  • Molecular Structure
  • Orobanchaceae / chemistry*
  • Rabbits
  • Sheep

Substances

  • Complement Inactivator Proteins
  • Drugs, Chinese Herbal
  • Glycosides
  • anticomplement