Delays in the diagnosis of pulmonary tuberculosis in Coahuila, Mexico

Int J Tuberc Lung Dis. 2012 Sep;16(9):1193-8. doi: 10.5588/ijtld.11.0476. Epub 2012 Jun 28.

Abstract

Objective: To determine diagnostic delay in pulmonary tuberculosis (PTB) cases and analyse associated factors.

Methods: New PTB cases were studied in Coahuila, Northern Mexico, between 2008 and 2009. We obtained census data and data on residential address, symptoms and diagnosis from the national patient database; sociodemographic variables were obtained during home visits. Bivariate analyses used the Kaplan-Meier method; multivariate analysis consisted of modelling survival.

Results: We studied 458 subjects (median age 48 years), who were predominantly males (56.1%); the median years of schooling was 6.0 years, 83.4% were urban residents, 50.3% were unemployed, and 87.7% suffered from food poverty. The median delay between the onset of symptoms and the first medical consultation was 53.5 days. Lack of formal education (P = 0.050) and living ≥5 km from a health unit (P = 0.034) were associated with longer delays and consequently with severe symptoms (cough ≥2 weeks, P = 0.001; chest pain, P = 0.032; malnutrition, P = 0.003). Mean health system delay (between first consultation and smear test result) was 18.5 days, and was significantly longer when the first consultation was with a private physician (P < 0.001) and when patient age was ≥46 years (P = 0.001).

Conclusions: In Coahuila, lack of formal education, living ≥5 km from a health unit, first consultation with a private physician, and being aged ≥46 years contributed to delays in PTB diagnosis.

MeSH terms

  • Adult
  • Age Factors
  • Antitubercular Agents / therapeutic use
  • Delayed Diagnosis*
  • Educational Status
  • Female
  • Health Services Accessibility
  • Healthcare Disparities
  • Humans
  • Kaplan-Meier Estimate
  • Logistic Models
  • Male
  • Mexico / epidemiology
  • Middle Aged
  • Multivariate Analysis
  • Mycobacterium tuberculosis / isolation & purification
  • Odds Ratio
  • Predictive Value of Tests
  • Private Practice
  • Referral and Consultation
  • Residence Characteristics
  • Risk Assessment
  • Risk Factors
  • Sputum / microbiology
  • Time Factors
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / microbiology
  • Tuberculosis, Pulmonary / mortality

Substances

  • Antitubercular Agents