Polyostotic Paget's disease

J Coll Physicians Surg Pak. 2012 Jul;22(7):461-3.

Abstract

Paget's disease of bone is a common metabolic bone disease in most of the European countries. The disease has distinct geographical distribution being rare in Asia. We report Paget's disease in a 70 years old Pakistani male who presented with history of pain in right leg with difficulty in walking for the last 5 months. Plain X-ray raised suspicion of Paget's disease of bone. Technetium-99m MDP bone scan showed involvement of multiple bones. Bone biopsy confirmed the diagnosis. This case illustrates that Paget's disease of bone does exist in Pakistan.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alendronate / therapeutic use
  • Alkaline Phosphatase / blood
  • Biopsy
  • Bone Density Conservation Agents / therapeutic use
  • Humans
  • Male
  • Osteitis Deformans / diagnostic imaging*
  • Osteitis Deformans / drug therapy
  • Osteitis Deformans / pathology
  • Radionuclide Imaging
  • Radiopharmaceuticals*
  • Technetium Tc 99m Medronate*
  • Tibia / diagnostic imaging*
  • Tibia / pathology
  • Treatment Outcome

Substances

  • Bone Density Conservation Agents
  • Radiopharmaceuticals
  • Alkaline Phosphatase
  • Alendronate
  • Technetium Tc 99m Medronate