Real-time flow with fast GPU reconstruction for continuous assessment of cardiac output

J Magn Reson Imaging. 2012 Dec;36(6):1477-82. doi: 10.1002/jmri.23736. Epub 2012 Jun 28.

Abstract

Purpose: To demonstrate the feasibility of real-time phase contrast magnetic resonance (PCMR) assessment of continuous cardiac output with a heterogeneous (CPU/GPU) system for online image reconstruction.

Materials and methods: Twenty healthy volunteers underwent aortic flow examination during exercise using a real-time spiral PCMR sequence. Acquired data were reconstructed in online fashion using an iterative sensitivity encoding (SENSE) algorithm implemented on an external computer equipped with a GPU card. Importantly, data were sent back to the scanner console for viewing. A multithreaded CPU implementation of the real-time PCMR reconstruction was used as a reference point for the online GPU reconstruction assessment and validation. A semiautomated segmentation and registration algorithm was applied for flow data analysis.

Results: There was good agreement between the GPU and CPU reconstruction (-0.4 ± 0.8 mL). There was a significant speed-up compared to the CPU reconstruction (15×). This translated into the flow data being available on the scanner console ≈9 seconds after acquisition finished. This compares to an estimated time using the CPU implementation of 83 minutes.

Conclusion: Our heterogeneous image reconstruction system provides a base for translation of complex MRI algorithms into clinical workflow. We demonstrated its feasibility using real-time PCMR assessment of continuous cardiac output as an example.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Algorithms
  • Aorta / anatomy & histology
  • Aorta / physiology*
  • Blood Flow Velocity / physiology
  • Cardiac Output / physiology*
  • Computer Graphics / instrumentation*
  • Computer Systems
  • Equipment Design
  • Female
  • Humans
  • Image Enhancement / instrumentation
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / instrumentation*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging, Cine / instrumentation*
  • Magnetic Resonance Imaging, Cine / methods*
  • Male
  • Middle Aged
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted / instrumentation