Effect of bone swaging with calcium phosphate bone cement on periodontal regeneration in dogs

Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jul;114(1):35-42. doi: 10.1016/j.tripleo.2011.05.028. Epub 2011 Aug 24.

Abstract

Objectives: The present study evaluated the effects of bone swaging (BS) with injectable calcium phosphate bone cement (CPC) on periodontal healing in 1-wall intrabony defects in dogs.

Study design: Surgically created 1-wall intrabony defects were treated with BS, CPC, BS with CPC (BS/CPC), or open-flap debridement (OFD). The animals were humanely killed for histologic evaluation at 8 weeks.

Results: New bone formation occurred from the host bone toward the coronal region of the defects in the BS/CPC group. The height of new bone formation was significantly higher in the BS/CPC group than in the other groups (P < .05). New cementum formation was most notable in the BS/CPC group, where it was significantly greater than in the OFD and CPC groups (P < .05).

Conclusions: Within the limitations of the present study, it was concluded that BS/CPC treatment effectively promoted new bone and cementum formation in 1-wall intrabony defects in dogs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Animals
  • Bone Cements / pharmacology*
  • Bone Regeneration / drug effects*
  • Calcium Phosphates / pharmacology*
  • Dogs
  • Guided Tissue Regeneration, Periodontal / methods*
  • Male
  • Mandible / drug effects
  • Mandible / surgery*
  • Periodontium / drug effects
  • Wound Healing / drug effects

Substances

  • Bone Cements
  • Calcium Phosphates