Purpose of review: This article aims to make a review of the up-to-date knowledge on anaphylaxis and outline the recent advances on pathophysiology, diagnosis, and management of anaphylaxis.
Recent findings: New data confirm the increase in prevalence of anaphylaxis and emphasize immunopathologic mechanisms. However, anaphylaxis is often underdiagnosed and guidelines are poorly applied, particularly in emergency departments.
Summary: An improvement of rapid diagnosis and treatment combined with education of population will decrease mortality and morbidity of anaphylaxis.