Structure-based tuning of T(m) in lipid-like ionic liquids. Insights from Tf2N- salts of gene transfection agents

Chem Commun (Camb). 2012 Aug 4;48(60):7522-4. doi: 10.1039/c2cc33609j. Epub 2012 Jun 25.

Abstract

Ionic liquids of cations bearing two lipid-like aliphatic tails are shown to have values of T(m) that can be very low, and that can be tuned up or down by the addition, deletion, or combination of dipolar modules and side-chain double bonds.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Calorimetry, Differential Scanning
  • Imidazoles / chemistry
  • Ionic Liquids / chemistry*
  • Lipids / chemistry*
  • Salts / chemistry*
  • Sulfonamides / chemistry*
  • Transfection
  • Transition Temperature

Substances

  • Imidazoles
  • Ionic Liquids
  • Lipids
  • Salts
  • Sulfonamides
  • bis(trifluoromethanesulfonyl)amide