Abstract
Plant stem cells in the shoot apical meristem (SAM) possess the unique abilities of both self-renewal for SAM maintenance and providing undifferentiated daughter cells for initiation and subsequent development of aerial organs. The coordination between stem cell renewal and cell differentiation during organogenesis is regulated by elaborate genetic pathways involving numerous transcription factors and other molecules. In the past decade, microRNAs (miRNAs) have emerged as pivotal regulators in many biological processes including meristem homeostasis and differentiation in plants. In this review, we summarize current knowledge about the function and mechanism of a family of miRNAs (miR165/166), the miRNA-designated Argonautes (AGOs), and the miRNA-regulated targets in SAM development and maintenance.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Arabidopsis / genetics
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Arabidopsis / growth & development
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Arabidopsis / metabolism
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Arabidopsis Proteins / genetics
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Arabidopsis Proteins / metabolism*
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Argonaute Proteins / genetics
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Argonaute Proteins / metabolism*
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Gene Expression Regulation, Plant
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Genes, Plant
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Homeodomain Proteins / genetics
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Homeodomain Proteins / metabolism
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Meristem / genetics
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Meristem / growth & development*
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Meristem / metabolism
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MicroRNAs / genetics
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MicroRNAs / metabolism*
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Plant Cells / metabolism
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Plant Shoots / genetics
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Plant Shoots / growth & development
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Plant Shoots / metabolism*
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Protein Structure, Tertiary
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RNA, Plant / genetics
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RNA, Plant / metabolism*
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RNA-Binding Proteins / genetics
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RNA-Binding Proteins / metabolism
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Transcription, Genetic
Substances
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AGO1 protein, Arabidopsis
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AGO10 protein, Arabidopsis
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Arabidopsis Proteins
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Argonaute Proteins
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HD-Zip protein, Arabidopsis
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Homeodomain Proteins
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MicroRNAs
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RNA, Plant
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RNA-Binding Proteins