Radiotherapy and bevacizumab for intramedullary and leptomenigeal metastatic glioblastoma: a case report and review of the literature

Int J Neurosci. 2012 Nov;122(11):691-4. doi: 10.3109/00207454.2012.704456. Epub 2012 Aug 8.

Abstract

Glioblastoma (GBM) developed metastases rarely and the prognosis, in these cases, was very poor. We reported a 30-year patient who, developing intramedullary and leptomeningeal metastases from GBM, underwent palliative spinal radiotherapy (RT) and Bevacizumab.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Angiogenesis Inhibitors / administration & dosage
  • Antibodies, Monoclonal, Humanized / administration & dosage*
  • Bevacizumab
  • Brain Neoplasms / pathology
  • Brain Neoplasms / surgery
  • Brain Neoplasms / therapy*
  • Chemoradiotherapy / methods*
  • Glioblastoma / secondary
  • Glioblastoma / surgery
  • Glioblastoma / therapy*
  • Humans
  • Male
  • Meningeal Neoplasms / secondary
  • Meningeal Neoplasms / surgery
  • Meningeal Neoplasms / therapy*
  • Spinal Cord Neoplasms / secondary
  • Spinal Cord Neoplasms / surgery
  • Spinal Cord Neoplasms / therapy*

Substances

  • Angiogenesis Inhibitors
  • Antibodies, Monoclonal, Humanized
  • Bevacizumab