In the title compound, C(14)H(13)ClN(2)O(5)S(2), the dihedral angles between the central benzene ring and the pendant chloro-benzene ring and the N-acetyl group are 82.35 (5) and 79.71 (6)°, respectively, and the overall conformation of the mol-ecule approximates to a U shape. Both the C-S-N-C conformations are gauche, but with opposite senses [torsion angles = -59.29 (15) and 63.68 (16)°]. An intra-molecular C-H⋯O inter-action generates an S(6) ring. In the crystal, inversion dimers linked by pairs of N-H⋯O hydrogen bonds generate R(2) (2)(20) loops. A second N-H⋯O hydrogen bond links the dimers into (101) layers.