Bioinspired ion-transport properties of solid-state single nanochannels and their applications in sensing

Chemphyschem. 2012 Jul 16;13(10):2455-70. doi: 10.1002/cphc.201200057. Epub 2012 Jun 19.

Abstract

Biological ion channels are able to control ion-transport processes precisely because of their intriguing properties, such as selectivity, rectification, and gating. Learning from nature, scientists have developed a promising system--solid-state single nanochannels--to mimic biological ion-transport properties. These nanochannels have many impressive properties, such as excess surface charge, making them selective; the ability to be produced or modified asymmetrically, endowing them with rectification; and chemical reactivity of the inner surface, imparting them with desired gating properties. Based on these unique characteristics, solid-state single nanochannels have been explored in various applications, such as sensing. In this context, we summarize recent developments of bioinspired solid-state single nanochannels with ion-transport properties that resemble their biological counterparts, including selectivity, rectification, and gating; their applications in sensing are also introduced briefly.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Biomimetics / instrumentation
  • Biomimetics / methods*
  • Biosensing Techniques*
  • Cations, Divalent / analysis
  • Cations, Monovalent / analysis
  • Ion Channel Gating
  • Ion Channels / chemistry*
  • Ion Transport
  • Microelectrodes
  • Microfluidic Analytical Techniques
  • Molecular Sequence Data
  • Nanostructures / chemistry*
  • Static Electricity
  • Surface Properties
  • Zinc Fingers

Substances

  • Cations, Divalent
  • Cations, Monovalent
  • Ion Channels